NCT06544616

Who might be able to join this trial:

• A brain scan (called a tau PET scan) has shown an elevated level of a protein called tau, which is associated with Alzheimer's disease, above a certain threshold
• You currently have no signs of memory or thinking problems, as measured by a standard assessment called the CDR (your score must be 0)
• You scored 27 or higher on a standard memory and thinking test called the MMSE (with some adjustment based on your level of education)
• You are able to read and write and have had at least 5 years of formal schooling
• You are not able to become pregnant (confirm with trial site for specific requirements)

Who may not be able to join:

• You have a known or suspected inherited (genetic) form of Alzheimer's disease that runs in the family
• You have already been diagnosed with Alzheimer's dementia or another type of dementia (such as Lewy body dementia, frontotemporal dementia, vascular dementia, or Parkinson's dementia, among others)
• You have already been diagnosed with Mild Cognitive Impairment (MCI), which is a recognised early stage of memory or thinking decline
• Your blood tests show low levels of Vitamin B12 or folate, unless the study doctor decides this does not need to be treated during the trial
• You have a neurological (brain or nervous system) condition other than early/preclinical Alzheimer's disease that could make it hard to interpret any new symptoms that appear during the study

Important: Always verify eligibility with the trial site directly before applying.