NCT05875233

Who might be able to join this trial:

• You are a woman between 18 and 36 years old.
• You have been diagnosed with polycystic ovary syndrome (PCOS) within the last 5 years.
• You have experienced at least two of the following: irregular or absent periods; excessive facial or body hair, thinning or lost scalp hair, oily skin, or acne; or polycystic ovaries confirmed by an ultrasound scan.
• You are generally healthy and do not have any long-term illness that is uncontrolled or unstable.
• You have concerns about any of the following: irregular periods or ovulation, mood swings, stress, breast tenderness, food cravings, irritability, or low energy.
• You have been following a steady, consistent diet and exercise routine, and are willing to keep that the same for the whole study.
• You are willing to avoid taking any other supplements that could affect your menstrual cycle during the study.
• You are willing and able to follow the study plan, including taking supplements at set times, filling in questionnaires online, and sharing photos where required.
• You are able to communicate in English.
• You are willing to sign a consent form agreeing to take part.
• If joining the hormonal birth control group: you have been using the same hormonal birth control for at least the past 3 months and are willing to keep using it unchanged for the next 6 months.
• If joining the non-hormonal birth control group: you have not used hormonal birth control for the past 3 months, are willing to stay off it for the next 6 months, and experience hormonal or frequent acne breakouts.

Who may not be able to join:

• You have any unstable, uncontrolled, or pre-existing medical or mental health condition.
• You have been diagnosed with any of the following: endometriosis, uterine fibroids, pelvic inflammatory disease, reproductive cancers, chronic liver disease, diverticular disease, colorectal cancer (or a past history of it), chronic pancreatitis, adenomyosis, fibromyalgia, rheumatoid arthritis, lupus, inflammatory bowel disease, chronic uncontrolled migraines, chronic pelvic pain syndrome, multiple sclerosis, or chronic fatigue syndrome.
• You have had your uterus removed (hysterectomy), both ovaries and fallopian tubes removed, or any other gynaecological procedure in the past 6 months.
• You have significant abnormal results from a physical check-up or blood tests, including kidney or liver function levels more than twice the normal range.
• You have a history of severe allergic reactions requiring an epi-pen, or you are allergic to any ingredient in the study supplement.
• You are currently pregnant, breastfeeding, or trying to become pregnant.
• You are unwilling or unable to follow the study plan.
• You are currently using any medication, herbal remedy, or supplement that can affect your menstrual cycle, or you have previously used the products "Elix Daily Harmony" or "Cycle Balance."
• You have started any new medication, supplement, or herbal remedy aimed at weight, skin (acne), mood, or your menstrual cycle within the last 3 months.
• You currently smoke or have smoked in the past 6 months.
• You have a history of substance abuse.
• You regularly drink more than 3 alcoholic drinks per day.
• Your BMI (a measure of body weight relative to height) is over 35.
• If joining the hormonal birth control group: you have changed your hormonal birth control in the past 3 months or plan to change it in the next 6 months.
• If joining the non-hormonal birth control group: you have used hormonal birth control in the past 3 months or plan to start using it in the next 6 months.

Important: Always verify eligibility with the trial site directly before applying.