NCT03713957

Who might be able to join this trial:

• You have been diagnosed with Parkinson's Disease and have had symptoms for at least 1 year.
• You have been diagnosed with Parkinson's Disease along with mild memory or thinking problems, or Parkinson's-related dementia, based on recognized medical guidelines.
• Your score on a standard memory and thinking test (called the MoCA) falls between 13 and 25.
• Your Parkinson's symptoms are rated at a mild to moderately advanced stage (stages 1–4 on a standard scale used by doctors).
• Your score on a test that helps rule out stroke-related thinking problems is 4 or below (confirm with trial site).

Who may not be able to join:

• You have a history of problems with blood clotting or your blood clotting too easily.
• You are currently taking blood-thinning medication (note: common blood-thinning tablets like aspirin or clopidogrel are generally acceptable).
• You have previously had an allergic reaction to any human blood product or any medication given through a drip (IV infusion).
• You have received a human blood product, including a blood transfusion or IV immunoglobulin therapy, in the 6 months before joining the trial.
• You have a history of certain immune system deficiencies, or have previously had a stroke, severe allergic reaction, or blood clot complications related to IV immunoglobulin treatment (confirm with trial site).
• You have had a heart attack, unstable or severe chest pain, or heart failure in the 6 months before the trial begins.
• Your blood count (haemoglobin level) is too low — below a certain level for women or men respectively (confirm exact values with trial site).

Important: Always verify eligibility with the trial site directly before applying.