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This trial is complete. It is no longer accepting participants. Results may be available on ClinicalTrials.gov.

NCT03365791

NCT03365791
Completed Phase 2

Who may be able to join

Who might be able to join this trial:

  • You have already received at least one previous treatment for your cancer, but no more than five previous treatments in total.
  • You have been diagnosed with a solid tumour or a type of lymphoma (called Diffuse Large B-cell Lymphoma) that has been confirmed by a pathology test, and your cancer can be measured using medical scans.

Who may not be able to join:

  • You have had a severe allergic reaction to a type of medication called a monoclonal antibody in the past.
  • You have significant heart problems or a condition that affects how well your heart works.
  • You currently have, or are suspected to have, an autoimmune disease (where the immune system attacks the body), or you have had one within the last three years — though some exceptions may apply (confirm with trial site).
  • You have a second, separate cancer that was diagnosed within the last three years before starting the trial.
  • You have previously been treated with certain immunotherapy medicines that target proteins called PD-1, PD-L1, CTLA-4, or LAG-3 — though people who had skin or hormone side effects from PD-1/PD-L1 treatment and were successfully treated for those may not be automatically excluded (confirm with trial site).

Important: Always verify eligibility with the trial site directly before applying.

Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.

Phase 2: approximately ~30% of drugs entering this phase reach regulatory approval, based on published industry-wide historical data. This is not specific to this trial.

Trial details

Status
Completed
Phase
Phase 2
Sponsor
Novartis Pharmaceuticals
Registry
clinicaltrials_gov
Start date
24 January 2018
Est. completion
21 February 2019

Where this trial is recruiting

🇺🇸 United States

Primary endpoints

Clinical Benefit Rate (CBR) at 24 Weeks of PDR001+LAG525 by Tumor Type in Multiple Solid Tumors and Lymphoma

Can't join this trial?

Expanded access pathways

If this trial is not available to you, other access pathways may exist. In Australia, the TGA Special Access Scheme allows access to unapproved therapeutic goods for individual patients.

TGA Special Access Scheme information

Find other recruiting trials on ClinicalTrials.gov

Data last synced from ClinicalTrials.gov: 30 June 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.

View original record on ClinicalTrials.gov