NCT02791191
Who may be able to join
Who might be able to join this trial:
- A qualified doctor has diagnosed you with mild Alzheimer's disease dementia based on recognised medical guidelines.
- You scored between 20 and 26 (inclusive) on a standard memory and thinking test called the Mini-Mental State Examination at your screening appointment.
- A special brain scan (called a florbetapir PET scan) showed signs of a protein buildup in the brain linked to Alzheimer's disease.
Who may not be able to join:
- You have a significant brain or nervous system condition other than Alzheimer's, such as another type of dementia, a serious brain infection, Parkinson's disease, multiple concussions, or epilepsy or repeated seizures (childhood febrile seizures may be an exception — confirm with trial site).
- You have an eye condition that would make it difficult to reliably test your vision or examine the back of your eye.
- You are currently taking certain strong medications that affect how the body breaks down drugs through a liver enzyme called CYP3A (confirm with trial site which medications apply).
- You have a known sensitivity or allergic reaction to florbetapir or a related substance called ¹⁸F-AV-1451, which are used in the brain scans.
- You are unable to have an MRI or PET scan, or you have very difficult-to-access veins for blood tests.
Important: Always verify eligibility with the trial site directly before applying.
Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.
Trial details
Where this trial is recruiting
10 site(s) in Australia. Confirm current status and contact details directly with the trial site.
Primary endpoints
Change From Baseline in ¹⁸F-AV-1451 Positron Emission Tomography (PET) Standard Uptake Value Ratio (SUVr) at 52 Weeks
Can't join this trial?
Data last synced from ClinicalTrials.gov: 30 June 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.