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This trial is complete. It is no longer accepting participants. Results may be available on ClinicalTrials.gov.

NCT01124435

NCT01124435
Completed Phase 2

Who may be able to join

Who might be able to join this trial:

  • You have been diagnosed with a returning (recurrent) cancer of the ovaries, fallopian tubes, or peritoneum of a specific type (serous carcinoma), and your cancer can be measured on scans.
  • You have previously been treated with a platinum-based chemotherapy as your first treatment, and have had at least one further round of chemotherapy since your cancer came back.
  • Your last platinum-based chemotherapy finished more than 6 months ago.
  • You are 18 years of age or older.
  • Your general health and ability to carry out daily activities falls within an acceptable range, as measured by a standard medical scale (confirm with trial site).
  • Your blood counts and bone marrow are working well enough (confirm with trial site).
  • Your kidneys and liver are functioning well enough (confirm with trial site).
  • You are willing and able to give written consent to take part in the study.

Who may not be able to join:

  • You have had an allergic reaction or sensitivity to celecoxib, aspirin, anti-inflammatory painkillers (such as ibuprofen), or sulfonamide drugs.
  • You have significant other health conditions, including active heart disease, heart failure, uncontrolled bleeding, severely high blood pressure, a stomach ulcer in the past 12 months, chronic bowel inflammation, a blood clot in a vein or artery in the past 12 months, or a history of a blood clot in the lungs.
  • You are currently taking other medications that could interact with the trial drugs (confirm with trial site).
  • You have had surgery, chemotherapy, or radiotherapy within the last month.
  • You are pregnant, could become pregnant, or are currently breastfeeding.
  • You have previously been treated with a COX-2 inhibitor drug as part of cancer treatment.
  • You have any psychological, social, or geographical circumstances that might make it difficult to follow the study schedule and attend follow-up appointments.

Important: Always verify eligibility with the trial site directly before applying.

Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.

Phase 2: approximately ~30% of drugs entering this phase reach regulatory approval, based on published industry-wide historical data. This is not specific to this trial.

Trial details

Status
Completed
Phase
Phase 2
Sponsor
Catholic University of the Sacred Heart
Registry
clinicaltrials_gov
Start date
1 October 2003
Est. completion
1 September 2007

Where this trial is recruiting

🇮🇹 Italy

Primary endpoints

Efficacy of the Combination Carboplatin plus Celecoxib in Heavily Pre-treated Recurrent Ovarian Cancer Patients

Can't join this trial?

Expanded access pathways

If this trial is not available to you, other access pathways may exist. In Australia, the TGA Special Access Scheme allows access to unapproved therapeutic goods for individual patients.

TGA Special Access Scheme information

Find other recruiting trials on ClinicalTrials.gov

Data last synced from ClinicalTrials.gov: 30 June 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.

View original record on ClinicalTrials.gov