NCT01041235

Who might be able to join this trial:

• You are able to read, understand, and sign an approved consent form agreeing to take part in the study.
• You have been diagnosed with a solid tumor that has been confirmed through a laboratory tissue test.
• Your cancer has continued to grow or spread after receiving standard chemotherapy, or there are no other suitable treatment options available to you.
• You have at least one tumor that can be measured or assessed using a CT or MRI scan.
• You are reasonably able to carry out daily activities (your doctor would assess this using a standard scale where a score of 2 or below is required).
• Your doctor expects you to live for at least 3 more months.
• You are 18 years old or older.
• If you are a woman who could become pregnant, you have a negative pregnancy test.
• Your liver is working well enough, based on blood test results that fall within acceptable ranges.
• Your kidneys are working well enough, based on blood test results that fall within acceptable ranges.
• Your blood counts (including white blood cells, platelets, and red blood cells) are at acceptable levels, measured within 3 days before your first dose.
• Your blood clotting levels are within an acceptable range.
• You have recovered well enough from any previous treatments (such as surgery, radiation, or chemotherapy) before starting the trial, as judged by the study doctor.
• You agree to use an effective form of contraception (such as hormonal methods, barrier methods, or abstinence) throughout the study and for 30 days after your last dose, if you or your partner could become pregnant.

Who may not be able to join:

• You have serious heart disease, have had a heart attack in the past 6 months, have an unstable heart rhythm, or show signs of reduced blood flow to the heart on a heart tracing (ECG).
• You have a seizure condition that requires medication to control it.
• You currently have active cancer that has spread to your brain or spinal cord — however, if you previously had brain/spinal metastases that were treated, you may still be eligible if you have been stable and symptom-free for at least 4 weeks, have scan evidence of this, and are either not taking steroids or have been on a steady steroid dose for at least 1 week (confirm with trial site).
• You have severe, long-term lung disease that causes low oxygen levels in your blood.
• You have an active bacterial, viral, or fungal infection that requires treatment with systemic medication (medicines that work throughout your whole body).
• You are currently pregnant or breastfeeding.
• You have had radiation therapy, surgery, chemotherapy, or another experimental treatment within the past 28 days before joining the study (or within 6 weeks if you received certain specific chemotherapy drugs — confirm with trial site).
• You are unwilling or unable to follow the procedures required by this study.
• You have a known history of HIV, hepatitis B, or hepatitis C infection.
• You have a serious non-cancer-related illness that, in the study doctor's opinion, could interfere with the goals of the trial.
• You are currently taking part in another clinical trial involving an experimental treatment.
• You have previously had an allergic reaction to docetaxel (a chemotherapy drug) or to a closely related drug or substance.

Important: Always verify eligibility with the trial site directly before applying.