NCT00869765

Who might be able to join this trial:

• You previously took part in a specific earlier study (called HREC 07305), which tested a brain stimulation treatment for depression, and you completed that study fully.
• At the end of that earlier study, your depression did not fully go away (measured by a standard depression score), OR your depression came back within one month of finishing that study.

Who may not be able to join:

• You have ever been diagnosed with a psychotic disorder or obsessive compulsive disorder at any point in your life, or you currently have (or have had in the past year) an eating disorder or post-traumatic stress disorder, or you have been diagnosed with bipolar disorder or intellectual disability.
• You have had problems with drug or alcohol misuse or dependence in the last 3 months (this does not include nicotine or caffeine).
• Your current episode of depression did not improve after electroconvulsive therapy (a type of electric shock treatment) (confirm with trial site).
• You regularly take a type of sedative/anxiety medication called benzodiazepines, and it would not be safe for you to stop taking them.
• Your depression is so severe right now that you need a very fast-acting treatment, for example because of dangerously poor nutrition, psychosis, or a high risk of suicide.
• You have a neurological condition or have had a brain injury — for example, a recent stroke — that could make brain stimulation unsafe for you.
• You have any metal in your skull, holes or defects in your skull, or skin problems such as cuts, sores, or a rash on your scalp where the treatment electrodes would be placed.
• You are a woman who is pregnant, or who could become pregnant and is not using reliable contraception (a urine pregnancy test will be done).

Important: Always verify eligibility with the trial site directly before applying.