Back to Ovarian Cancer
NCT00710762
NCT00710762
Who may be able to join
Who might be able to join this trial:
- You are a woman who has been diagnosed (confirmed by lab testing) with advanced ovarian cancer, fallopian tube cancer, or primary peritoneal cancer of the serous type that has come back, and your cancer responded to your 2nd, 3rd, or 4th round of chemotherapy.
- Your cancer responded to treatment, meaning your CA125 blood marker dropped by at least 50%, or your tumors shrank or disappeared based on scans.
- Less than 12 months have passed since you started your most recent chemotherapy for your returned cancer.
- You have fully recovered, or recovered as much as possible, from the side effects of any previous chemotherapy or radiation treatment.
- You are older than 18 years of age.
- Your doctor expects you to live for at least 3 more months.
- You are well enough to carry out normal daily activities with little or no difficulty (confirm with trial site).
- Your liver is working well enough, based on blood test results within accepted ranges.
- Your kidneys are working well enough, based on blood test results within accepted ranges.
- Your blood counts (white blood cells, platelets, and hemoglobin) are at acceptable levels.
- You are willing and able to sign a written consent form agreeing to take part in the trial.
- It has been more than 4 weeks but less than 8 weeks since your last chemotherapy, hormonal treatment (other than hormone replacement therapy), or immunotherapy.
Who may not be able to join:
- You have a serious illness or condition unrelated to cancer, such as a neurological, psychiatric, or infectious disease, active skin or stomach ulcers, or abnormal lab results that could make participation risky.
- You have had major surgery or a serious injury in the past 4 weeks and have not fully healed, or you are planning to have surgery during the study.
- You have had an allergic reaction to the study drug (BIBF 1120) or any of its ingredients before.
- You have significant heart or blood pressure problems, such as uncontrolled high blood pressure, unstable chest pain, a heart attack in the past 9 months, or moderate-to-severe heart failure.
- You have had a serious bleeding event or a blood clot in the past 12 months, or you have an inherited condition that increases your risk of bleeding or clotting.
- You currently need to take full-dose blood-thinning (anticoagulant) medication.
- You have a stomach or bowel condition that would prevent you from properly absorbing the study drug.
- Your cancer has spread to your brain or the lining around your brain or spinal cord.
- You have taken part in another clinical trial or received an experimental drug within the past 4 weeks, or are currently doing so.
- You have received chemotherapy, radiation, or immunotherapy within the past 4 weeks.
- You are unable or unwilling to follow the requirements of the study.
- You currently have an active problem with alcohol or drug misuse.
- You have had another type of cancer (other than certain minor skin cancers) within the past 5 years.
- You are not confirmed to be unable to become pregnant (confirm with trial site).
Important: Always verify eligibility with the trial site directly before applying.
Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.
Phase 2: approximately ~30% of drugs entering this phase reach regulatory approval, based on published industry-wide historical data. This is not specific to this trial.
Trial details
Status
Completed
Phase
Phase 2
Sponsor
Boehringer Ingelheim
Registry
clinicaltrials_gov
Start date
1 March 2006
Est. completion
1 September 2008
Where this trial is recruiting
🇬🇧 United Kingdom
Primary endpoints
PFS Rate at 36 Weeks (After 9 Months)
Can't join this trial?
Data last synced from ClinicalTrials.gov: 30 June 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.