NCT00455000

Who might be able to join this trial:

• You are male, or a female who is not able to become pregnant (for example, post-menopausal), and you are between 50 and 85 years old
• You have been diagnosed with probable Alzheimer's disease, confirmed using two specific sets of recognised medical guidelines (confirm with trial site)
• You scored between 16 and 26 (inclusive) on a standard memory and thinking test called the Mini-Mental State Exam
• You scored 4 or below on a test that helps doctors check whether thinking problems are related to blood flow in the brain, called the Rosen-Modified Hachinski Ischemia Score (confirm with trial site)

Who may not be able to join:

• You have been diagnosed with, or have a history of, any other type of dementia or brain-degenerative condition besides Alzheimer's disease
• You have been diagnosed with, or have a history of, significant problems with blood flow or blood vessels in the brain (such as a stroke)
• A brain scan (MRI) has shown certain specific findings, such as signs of a stroke, small bleeds in the brain, multiple small fluid-filled spaces, or large areas of changes in the white matter of the brain
• You have a history of a condition where your immune system attacks your own body (an autoimmune disorder)
• You have a history of serious allergic reactions, including severe reactions known as anaphylaxis

Important: Always verify eligibility with the trial site directly before applying.