NCT00086892

Who might be able to join this trial:

• You have been diagnosed with ovarian cancer or primary peritoneal cancer (confirmed by a lab test on tissue samples) that has come back after previous treatment
• Your cancer can be measured on a scan or by physical examination (there is at least one tumor large enough to be tracked)
• The tumor being measured is not in an area that was previously treated with radiation
• You previously received one round of chemotherapy containing a platinum-based drug (such as carboplatin or cisplatin) as your main treatment
• Your cancer responded to that platinum-based chemotherapy, and you had more than 6 months without signs of the cancer coming back before it returned
• In some cases, a treatment-free period of more than 12 months may be required depending on other available trials (confirm with trial site)
• A tissue sample from your tumor (either a tissue block or slides) is available for research
• You are 18 years of age or older
• You are well enough to carry out everyday activities with little or no limitation (confirm with trial site)
• Your blood counts are at acceptable levels — enough white blood cells and platelets
• Your liver and kidney function are within acceptable ranges based on blood tests
• You have had a negative pregnancy test (if applicable)
• If you are able to become pregnant, you are willing to use effective birth control during the trial

Who may not be able to join:

• Your cancer has not come back — this trial is only for recurrent disease
• You have already received chemotherapy specifically to treat the cancer after it came back
• You have no measurable tumor that can be tracked on a scan or by examination
• You have uncontrolled high blood pressure
• You have unstable chest pain (angina), heart failure, or an uncontrolled irregular heartbeat within the past 6 months
• You have another significant heart condition
• You have an uncontrolled seizure disorder or an active neurological (brain or nerve) disease
• You have significant nerve damage or numbness/tingling beyond a mild level
• You have had another serious cancer (other than certain common skin cancers) within the past 5 years
• You have an active infection that requires antibiotic treatment
• You are pregnant or breastfeeding
• You have previously been treated with certain targeted therapies that affect a protein called EGFR (epidermal growth factor receptor), including specific antibody treatments or tyrosine kinase inhibitor drugs
• You have previously received a type of antibody therapy called a chimerized or murine monoclonal antibody
• You have received radiation to more than 25% of the areas of your body where bone marrow is produced
• You have had major surgery within the past 30 days and have not yet fully recovered
• You are currently taking part in another experimental treatment study
• You may be eligible for a higher-priority trial within the same research group (confirm with trial site)

Important: Always verify eligibility with the trial site directly before applying.