NCT00020696

Who might be able to join this trial:

• You have been diagnosed with ovarian cancer or primary peritoneal cancer that has been confirmed by a tissue sample (biopsy), and it has either persisted or come back after treatment
• Your cancer can be measured on a scan — at least 20mm using standard imaging, or at least 10mm using a spiral CT scan
• Your cancer responded to a platinum-based chemotherapy (such as cisplatin) and then stayed away for more than 6 months before coming back
• You have had one prior chemotherapy treatment that included a platinum-based drug for your original diagnosis
• If you have never had paclitaxel (a common chemotherapy drug), you may have had a second round of treatment that included it
• Your general health and ability to carry out daily activities meets the study's fitness requirements (confirm with trial site)
• Your blood counts are at a healthy enough level — specifically, your white blood cells and platelets are above certain minimum levels
• Your liver and kidney function tests are within an acceptable range
• You have fully recovered from any previous chemotherapy, radiation, or surgery

Who may not be able to join:

• Your cancer has not responded to platinum-based chemotherapy, or it came back within 6 months of finishing that treatment
• You have had more than one chemotherapy regimen for recurring or returning cancer (beyond what is specified above)
• You have had a heart attack or heart disease at any point in the past or currently
• You currently have an active infection that requires antibiotic treatment
• You have significant nerve damage causing numbness, tingling, or weakness beyond a mild level
• You have had another serious cancer (other than certain common skin cancers) within the last 5 years
• You are currently pregnant, or a pregnancy test comes back positive
• You are able to become pregnant but are unwilling to use effective birth control during the trial
• You have previously been treated with a drug called tirapazamine
• You have previously had radiation therapy to the areas of cancer being measured in this trial
• You have had radiation to more than 25% of your bone marrow in the past
• You are eligible for a higher-priority related clinical trial that is currently open (confirm with trial site)
• You have had any other cancer treatment that would interfere with taking part in this study (confirm with trial site)

Important: Always verify eligibility with the trial site directly before applying.