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This trial is complete. It is no longer accepting participants.

NCT00004811

NCT00004811
Completed Phase 2

Who may be able to join

Who might be able to join this trial:

  • You have a confirmed fungal infection (proven by a lab culture), specifically chronic cavitary histoplasmosis, histoplasmosis that has spread outside the lungs (such as affecting mucous membranes), blastomycosis, or sporotrichosis
  • Your lab culture still showed the fungal infection after your last round of treatment
  • Your doctor has determined you need antifungal treatment with amphotericin B or ketoconazole
  • It has been at least 1 month since you last received treatment for this same fungal infection
  • You have received no more than a certain limited total amount of amphotericin B or ketoconazole in the past (confirm with trial site for exact amounts)
  • Your liver function test results are within an acceptable range (confirm with trial site)

Who may not be able to join:

  • You have a fungal infection affecting the membranes around your brain or spinal cord (fungal meningitis)
  • You have any disease affecting your brain or central nervous system
  • Your fungal infection is immediately life-threatening
  • You are currently taking medications that suppress your immune system, such as corticosteroids, azathioprine, or chemotherapy-type drugs
  • You have HIV/AIDS
  • You are pregnant or currently breastfeeding
  • You are able to have children but are not using effective birth control

Important: Always verify eligibility with the trial site directly before applying.

Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.

Phase 2: approximately ~30% of drugs entering this phase reach regulatory approval, based on published industry-wide historical data. This is not specific to this trial.

Trial details

Status
Completed
Phase
Phase 2
Sponsor
National Center for Research Resources (NCRR)
Registry
clinicaltrials_gov
Start date
1 March 1985

Can't join this trial?

Expanded access pathways

If this trial is not available to you, other access pathways may exist. In Australia, the TGA Special Access Scheme allows access to unapproved therapeutic goods for individual patients.

TGA Special Access Scheme information

Find other recruiting trials on ClinicalTrials.gov

Data last synced from ClinicalTrials.gov: 30 June 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.

View original record on ClinicalTrials.gov