NCT00004800

Who might be able to join this trial:

• Newborns being enrolled at their first vaccine clinic visit
• Baby girls who weigh between 3.2 and 3.8 kg at their first vaccination
• Baby boys who weigh between 3.4 and 4.0 kg at their first vaccination
• Babies who are older than 6 weeks but younger than 12 weeks of age
• Babies who have never shown signs of whooping cough (pertussis)
• Babies who have never received a whooping cough vaccine before
• Babies whose mother speaks Italian and can be reached by phone
• Babies whose family plans to stay in the local clinic area for at least 1 year

Who may not be able to join:

• Babies who have previously been vaccinated against whooping cough
• Babies who have had kidney (renal) failure
• Babies who have received long-term medication that suppresses the immune system
• Babies who have taken steroid medicines (corticosteroids) for 14 days or more, or who received them within the last 48 hours
• Babies born with a major physical abnormality
• Babies who are not growing or gaining weight as expected (sometimes called "failure to thrive")
• Babies with a known or possible problem with their immune system — for example, if their mother is HIV-positive, or if the baby has certain blood or immune conditions (confirm with trial site)
• Babies who have had brain or nervous system problems around the time of birth
• Babies who have had seizures (convulsions)

Important: Always verify eligibility with the trial site directly before applying.