NCT00004665

Who might be able to join this trial:

• You have been diagnosed with systemic lupus erythematosus (lupus) based on recognised medical criteria
• Your lupus is considered mild to moderate
• You are currently taking prednisone (or a similar steroid) at a dose between 10 and 30 mg per day
• Either you tried to reduce your prednisone dose in the last 12 months but were unable to, and your dose has been stable for at least 6 weeks — OR you have not tried to reduce your dose in the last 12 months and your dose has been stable for at least 3 months
• You have previously completed a study involving a supplement called DHEA (dehydroepiandrosterone)
• You are a woman aged 18 or older
• If you are able to become pregnant, you have a negative pregnancy test within 2 weeks before joining, and you are using reliable contraception

Who may not be able to join:

• You previously took part in a double-blind DHEA study at Stanford University
• You are currently taking immune-suppressing medications
• You are currently taking part in another clinical study
• You have taken any experimental treatment within the last 30 days (or longer, depending on the specific medication) (confirm with trial site)
• You have taken certain immune-suppressing drugs — including cyclophosphamide, azathioprine, or intravenous immunoglobulin — within the last 3 months
• You have changed your dose of anti-inflammatory drugs (such as ibuprofen) or hydroxychloroquine within the last month
• You have a known allergy or sensitivity to DHEA, cornstarch, lactose, or magnesium stearate
• You have any condition that would make it difficult for you to follow the study requirements
• You have a history of breast cancer or cancer of the reproductive organs
• You are using an oral contraceptive that contains oestrogen
• You are male

Important: Always verify eligibility with the trial site directly before applying.