NCT00004399

Who might be able to join this trial:

• You have been diagnosed with severe preeclampsia (a serious pregnancy complication) and are at risk of seizures
• Your blood pressure is higher than 160/110 mmHg, or your average arterial blood pressure reading is 126 mmHg or above
• Your urine tests show a large amount of protein (more than 5 grams over 24 hours)
• You have pain in your upper abdomen or upper right side, or your liver enzyme levels are significantly elevated (confirm with trial site)
• You have severe headaches and/or visual disturbances such as blind spots
• Your blood platelet count is very low (below 100,000), or you have signs of abnormal blood clotting or red blood cell damage
• Your urine output is very low (less than 400 mL per day or 30 mL per hour)
• You have fluid buildup in your lungs (pulmonary edema)

Who may not be able to join:

• You have previously used or are currently using magnesium sulfate or a type of blood pressure medication called dihydropyridines
• You are currently taking any other anti-seizure medications
• You have severe kidney failure
• You have a history of chest pain (angina) or a heart attack
• You have any heart problems or abnormal heart rhythms, particularly a heart rate below 60 beats per minute
• You have a history or signs of heart failure
• You have a serious mental or physical condition that could affect your treatment
• You are allergic to drugs with a similar chemical structure to nimodipine or magnesium sulfate
• There are signs of distress or abnormalities detected in your unborn baby

Important: Always verify eligibility with the trial site directly before applying.