NCT00004397

Who might be able to join this trial:

• You have been diagnosed with acute intermittent porphyria, variegate porphyria, or hereditary coproporphyria
• Your condition causes 6 or more attacks (flare-ups) per year
• If you are already receiving preventive heme therapy, you have had fewer than 2 attacks in the past 6 months
• During an acute attack, your urine test shows a specific marker (called porphobilinogen) at a level of at least 20 mg over 24 hours

Who may not be able to join:

• You are currently pregnant
• You are able to become pregnant but are unwilling to use effective birth control during the trial and for 6 months before joining
• Your symptoms are caused by another illness, not porphyria
• You have had continuous symptoms of porphyria lasting longer than one month, unless those ongoing symptoms also include separate acute flare-ups on top of them
• You have an active bleeding condition, such as bleeding in the digestive tract or bleeding in the brain
• You have a known allergy or sensitivity to tin mesoporphyrin (the treatment being studied)
• You have a known allergy or sensitivity to any intravenous (IV) heme preparation
• You have another medical condition that may put you at increased risk during the trial (confirm with trial site)

Important: Always verify eligibility with the trial site directly before applying.